Born into the desolation of a working-class family, Lacasse's artistic vocation was first outlined at the local stone quarries where he worked as a young teenager. During 1910-12, Lacasse intuitively established his search for light, extracted from the glistening rock. In 1925, Lacasse moved to Paris where he became known as a painter of religious scenes. However, with Brancusi as his neighbour, Lacasse was inspired to revisit his teenage interest in light and the composition of rocks - this led him to make a series of small abstract paintings during the 1930s. His acquaintance with Robert Delaunay influenced his coloristic development.
Upon his return to Paris in 1946, after having spent the war years in Britain, Lacasse was offended by his years-long omission from the Parisian art market which had facilitated the rise in popularity of Serge Poliakoff. As of the early 1950s Sonia Delaunay came to Lacasse's defence writing on several occasions about Lacasse's influence on Poliakoff who visited Lacasse in the 1930's whilst still being a musician.

The works of Lacasse are included in the following museums: Musée d'Art Moderne de la Ville de Paris; Musée National d'Art Moderne; Centre Pompidou, Paris; Musée des Beaux-Arts, Brussels; Musée de Tournai, Tournai; Musée des Arts Décoratifs, Paris; Tel Aviv Museum of Art, Tel Aviv; Eilat Museum, Eilat; Carnegie Institute, Pittsburgh; National Gallery of Victoria, Melbourne.